Characterization of the Biosynthetic Gene Cluster of Goad- sporin which Promote Secondary Metabolism and Sporula- tion in Actinomycetes
نویسنده
چکیده
Goadsporin which was isolated from Streptomyces sp. TP-A0584 is a 19-amino-acid polypeptide containing four oxazole and two thiazole rings within its backbone (Fig. 1). Goadsporin promotes secondary metabolism and morphogenesis in actinomycetes. There are no related reports on the substance which induces the secondary metabolism and morphogenesis in a wide variety of different Streptomyces species. The research aims of this study are to identify and characterize the goadsporin biosynthetic gene cluster, and propose the mode of action of it.
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